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Reck M, et al. IMpower150 PFS analysis.

0

10

20

30

40

50

60

70

80

Arm B:

atezo + bev + CP

Arm C:

bev + CP

Response (%)

35

a

Investigator-assessed ORR.

b

Censored value.

Data cutoff: September 15, 2017

ORR

a

and DOR in ITT-WT and Teff-high WT

0

10

20

30

40

50

60

70

80

Arm B:

atezo + bev + CP

Arm C:

bev + CP

Response (%)

CR/PR:

1%/47%

CR/PR:

4%/60%

CR/PR:

2%/51%

CR/PR:

4%/65%

CR

PR

ORR: 48%

ORR: 64%

ORR: 54%

ORR: 69%

ITT-WT

Teff-high WT

CR

PR

Median DOR

(range), mo

9.0 (0.4-24.9

b

)

5.7 (0.0

b

-22.1)

Median DOR

(range), mo

11.2 (0.5-24.9

b

)

5.7 (0.0

b

-22.1)

Arm B:

atezo + bev + CP

Arm B:

atezo + bev + CP

Arm C:

bev + CP

Arm C:

bev + CP