30 / 42
0
3
6
9
12 15 18 21 24 27
0
10
20
30
40
50
60
70
80
90
100
Time, months
Overall Survival, %
60
57
55
51
46
44
36
22
7
1
63
58
57
51
43
39
29
18
9
0
No. at risk
Overall Survival
Data Cut-Off: May 31, 2017
•
a
24 additional deaths since primary analysis (pembro + PC, n = 7; PC alone, n = 17).
b
P value is descriptive (one-sided P < 0.025).
Median Follow-Up:
18.7 mo
Events,
n/N
HR (95%
CI)
Pembro + PC
20/60
a
0.59
(0.34–1.05)
P
= 0.03
b
PC alone
31/63
a
77%
69%
Median (95% CI)
NR (22.8–NR)
20.9 (14.9–NR)
70%
56%
Hossein Borghaei
, et al. WCLC 2017
Crossover
~
75%