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EXTREME: QoL
Mesía R, et al. Ann Oncol 2010;21:1967–1973
EORTC Quality of Life Questionnaire (QLQ)-C30; ≤55% of patients completed a
baseline questionnaire
*Platinum-based CT, consisting of cisplatin/carboplatin + 5-FU
†
At 6 months, after baseline adjustment
‡
Bars show 95% CIs
CT* alone
Cetuximab + CT*
Baseline
Cycle 3
6 months
CT alone:
n=94
n=63
n=20
Cetuximab + CT:
n=109
n=80
n=45
100
80
60
40
20
0
–20
Score (least-squares mean)
Difference between
treatment arms
‡
Global health status/QoL was not statistically different
between treatment arms at 6 months
p=0.28
†