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0

5

10

15

20

25

30

35

40

Response rate (%)

EXTREME: CTX incrementa la TR independientemente del tipo de platino

23.0

38.9

15.0

30.4

Cisplatin/

5-FU

(n=135)

Cisplatin/

5-FU +

cetuximab

(n=149)

Carboplatin/

5-FU

(n=80)

Carboplatin/

5-FU +

cetuximab

(n=69)

Cisplatin-based CT

p=0.0035

Carboplatin-based CT

p=0.0267

Vermorken JB. Springer Science+Business Media 2011:651–664

+15.9

+15.4