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Real-world Data: Chemotherapy

Unresectable and M1 disease

Cowey et al. Future Oncol. 2017, 13(19): 1699-1710; Becker et al. Oncotarget 2017, 8(45):79731-41

US Oncology Network

Data collection: electronic medical records

N=686 MCC IV=255

1L= 51

(67)

2L= 14

(20)

Primary endpoint: ORR

ORR 29.4%

mDoR 6.7m

mPFS 4.6m

ORR 28.6%

mDoR 1.7m

mPFS 2.2m

1L

2L

ORR 46.4.%

mDoR 3.3m

mPFS 4.7 m

ORR 10.3%

mDoR 1.9m

mPFS 3.0 m

1L

2L

German Cancer Research Centre , Austria, Switzerland

Data collection: Patient Registry

1L= 28

(32)

2L= 29

(34)

Primary endpoint: ORR

N=971 MCC IV=242