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Merkel Carcinoma: Prognosis
Moshiri . J Invest Dermatol. 2017 ; Paulson et al. J Clin Oncol 2011, 29:1539-46
N=282
Retrospective
Detection viral status:
•
MCPyV DNA by qPCR
•
Large T antigen by IHC
p
= 0.14
p
= 0.0052
Tumor Viral Status
N=35
Intratumoral CD8+ T cells and an immune response
gene signature predictors of good prognoses
N=146
Immune Status