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Unresectable and M1 Disease
Systemic Treatment
Chemotherapy: Platinum-based, taxanes, topotecan…
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No randomized clinical trials
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Most reports based on aggregate case studies and mixed-stage
populations
N=30 patients (2L)
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RR 23%
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mPFS 0.7m
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mOS 5.7m
Iyer et al. Cancer Med 2016, 5:2294-2301
Single center retrospective analysis
N=62 patients (1L)
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RR 55%
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mPFS 3.1m
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mOS 9.5m