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*TC3 or IC3: ≥50% of TCs or ≥10% of ICs; TC2/3 or IC2/3: ≥5% of TCs or ICs; TC1/2/3 or IC1/2/3: ≥1% of TCs or ICs;

TC0 and IC0: <1% of TCs and ICs

1. Brahmer, et al. N Engl J Med 2015; 2. Borghaei, et al. N Engl J Med 2015

3. Herbst, et al. Lancet 2015; 4. Barlesi, et al. ESMO 2016

PD-L1 does not predict efficacy

for all immune checkpoint

inhibitors in mNSCLC