

Sorafenib Treatment
Was Associated With
Significantly
Longer PFS
Vs
Placebo
n
Median PFS, mo
Sorafenib
207
10.8
Placebo
210
5.8
PFS Probability, %
Months From Randomization
0
5
10
15
20
25
30
0
10
20
40
60
80
100
30
50
70
90
HR = 0.59; 95% CI: 0.45-0.76
P
< 0.0001
PFS: Double-blind Period
1,2
(by Independent
Central Review
)
CI, confidence interval; HR, hazard ratio.
1. Brose MS, et al.
Lancet.
2014;384(9940):319-328. 2. Brose MS, et al. Presented at ASCO 2013.