

“
Por favor,
No
más Quimioterapia…
”
Gottlieb J and Stratton Hill C. N Engl J Med 1974: Shimaoka K, et al. Cancer, 1985
Doxorubicin
1
Year
1974
Number of patients
30
Design
Experience review
Clinical Benefit
37% partial remission
Unproven
OS, PFS, QOL, QALY cost
Predictive markers
-
3 months
Chemotherapy of Thyroid Cancer with Adriamycin — Experience with 30 Patients
Jeffrey A. Gottlieb, M.D., and C. Stratton Hill, Jr., M.D.
N Engl J Med 1974; 290:193-197