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SUNITINIB VS PLACEBO
IN ADVANCED PNET
Percentage of event-free
Time (months)
Censoring times
Sunitinib (n/N = 30/86)
Placebo (n/N = 51/85)
Kaplan-Meier median PFS
Sunitinib: 11.4 months
Placebo: 5.5 months
HR = 0.42 ; 95% CI [0.26-0.66]
P
value <.001;
nominal critical z value = 3.8506
0
5
10
15
20
25
86
85
39
28
19
7
4
2
0
1
0
0
Number at risk:
Sunitinib
Placebo
0
20
40
60
80
100
* Local review
Raymond E, et al.
N Engl J Med
. 2011