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PRRT
NETTER-1
Everolimus
RADIANT-3 & RADIANT-4
Somatostatin Analogues
PROMID / CLARINET
Unresectable NET
SI-NET
pNET
G1
Sunitinib
G2
G1
G2
Chemotherapy
LUNG NET
Everolimus
RADIANT-4
G1
G2
Chemotherapy
Interferon
ADVANCED NETS – THERAPEUTIC ALGORITHM
Caplin M et al., NEJM 2014; Rinke A et al., J Clin Oncol 2009; Yao et al., NEJM 2011;
Raymond et al. NEJM 2011; Strosberg J, et al. NEJM 2016; Yao JC, et al. Lancet 2016;
Somatostatin Analogues