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Patient Characteristics

Category

Subgroup

Eribulin (n=228)

n (%)

Dacarbazine (n=224)

n (%)

Histology

ADI

LMS

Other

75 (32.9)

152 (66.7)

1 (0.4)

78 (34.8)

145 (64.7)

1 (0.4)

ADI histological subtype Dedifferentiated

Myxoid/round cell

Pleomorphic

32 (14.0)

30 (13.2)

13 (5.7)

37 (16.5)

26 (11.6)

15 (6.7)

LMS primary site

Uterine

Nonuterine

67 (29.4)

85 (37.3)

62 (27.7)

83 (37.1)

Tumor grade

High

Intermediate

Not done

150 (65.8)

77 (33.8)

1 (0.4)

152 (67.9)

69 (30.8)

3 (1.3)

Number of prior

regimens for advanced

disease

0

1

2

>2

1 (0.4)

15 (6.6)

116 (50.9)

96 (42.1)

1 (0.4)

14 (6.3)

98 (43.8)

111 (49.6)

1. Schöffski P, et al. Presented at ASCO 2015 Annual Meeting, Chicago IL, June 3-7, 2015:abstr LBA10502

2. Schöffski P, et al. Lancet. 2016 Apr 16;387(10028):1629-37

There were no significant differences in baseline characteristics between the 2 treatment

arms