

•
Nintedanib inhibits all types of three key RTKs involved in
angiogenesis*
–
VEGFRs,
–
PDGFRs and
–
FGFRs
VEGFR=vascular endothelial growth factor receptor;
PDGFR=platelet-derived growth factor receptor; FGFR=fibroblast
growth factor receptor
*Hilberg F, et al.
Cancer Res
2008;68:4774–4782
Nintedanib: inhibidor triple angioquinasa