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LUME LUNG 1: Significant Improvement in Disease

Control Rate by Independent Central Review

Reck M, et al.

Lancet Oncol

. 2014;15:143-55.

CR = complete response; HR = hazard ratio; OR = odds ratio; OS = overall survival; PR = partial response; SD = stable disease; PD = progressive disease.

*Significant improvement in disease control rate with nintedanib + docetaxel

(Odds ratio 1.93;

P

<0.0001 for adenocarcinoma and Odds ratio 1.68,

P

<0.0001 for all patients)