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Time, months

Survival probability

0

2

4

6

8

10 12 14 16 18 20 22

0.0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0

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Progression free survival (PFS)

P+ET

(n=57)

P

(n=58)

n. events (%)

40 (70%)

50 (86%)

median PFS mo.

(95%CI)

10.8

(5.6; 12.7)

6.5

(5.4: 8.5)

p- value, exploratory

0.12

HR (95% CI)

0.69 (0.4; 1.1)

Number of subjects at risk

58

55

37

31

22

16

13

8

6

2

1

1

P:

57

54

37

30

30

22

17

13

10

8

5

3

P+ET:

Malorni L, et al. ASCO 2017