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Pan Cancer

Bladder

Breast

Colorectal

Esophagogastric

Glioma

Head and Neck

Melanoma

NSCLC

Ovarian

Renal Cell

1804

127

48

63

63

117

76

323

472

32

155

18

35

4

14

10

5

8

13

22

3

2

3.39e-08

0.032

0.025

0.067

0.059

0.105

0.028

3.34e-06

7.33e-03

6.44e-03

0.038

Cutoff

P Value

No Patients

Cancer Type

Chan, N

. ASCO Clinical Immuno-Oncology Symposium

2016

Improved Survival for Greater Mutations

HR Optimized Cutoff

0

0,5

1

1,5

2

2,5

3

IMPACT Platform, MSKCC

Pan-Cancer Analysis of TMB and

ICB response: MSK-IMPACT