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REVEL:

Overall Survival – ITT Population

527

501

415

386

329

306

231

197

156

129

103

86

70

56

45

36

23

23

11

9

2

0

RAM+DOC

PL+DOC

628

625

0

0

Number at Risk

Median (95% CI)

Censoring Rate

RAM+DOC

10.5 (9.5-11.2)

31.8%

PL+DOC

9.1 (8.4-10.0)

27.0%

RAM+DOC vs. PL+DOC

Stratified HR (95% CI)=0.86 (0.75-0.98)

p=.023

Garon E, et al. Lancet 2015