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OAK: OS by histology

Histology information from eCRF

*Unstratified HRs;

§

P

values for descriptive purpose only

Barlesi, et al. ESMO 2016 (Abs. LBA44)

OS in squamous

OS in non-squamous

0

1.0

0.8

0.6

0.4

0.2

0

1.0

0.8

0.6

0.4

0.2

0

0

6

27

12

24

18

3

9

15

21

Time (months)

Time (months)

OS estimate

6

27

12

24

18

3

9

15

21

7.7

8.9

11.2

15.6

HR=0.73*

(95% CI 0.54–0.98)

p=0.0383

§

Atezolizumab (n=112)

Docetaxel (n=110)

HR=0.73*

(95% CI 0.60–0.89)

p=0.0015

§

Atezolizumab (n=313)

Docetaxel (n=315)

Minimum follow-up 19 months