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NP28761 (USA)

NP28673 (Global)

1.0

0.8

0.6

0.4

0.2

0

PFS estimate

0

3

6

9

Time (months)

12

15

18

21

Median PFS 8.2 months

1.0

0.8

0.6

0.4

0.2

0

0

Time (months)

Alectinib 600mg

(n=138)

18

6

3

9

12

15

Median PFS 8.9 months

Alectinib 600mg BID

(n=87)

NP28761 data cut-off 27 April 2015; NP28673 data cut-off 8 Jan 2015

Shaw, et al. WCLC 2015; Ou, et al. ASCO 2015;

NP28761 and NP28673: PFS (ITT)