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Study

Design

Recruiting

Secondary

Endpoints

Study

Period

Primary

Endpoint

1

2

ACCRU RC1126 (NCT01532089)

USA

Phases III

Erlotinib+Bec vs

Erlotinib

EGFR Mut (+)

Recruiting

PFS

OS

ORR

Safety

2012–2017

BEVERLY

(NCT02633189)

Italy

2015 – 2018

OS

QoL

ORR

Phases III

Erlotinib+Bec vs

Erlotinib

EGFR Mut (+)

NEJ026

(UMIN000017069)

Japan

20

15–2018

Phases III

Erlotinib+Bec vs

Erlotinib

EGFR Mut (+)

ARTEMIS

(NCT02759614)

China

2016–2019

Phases III

Erlotinib+Bec vs

Erlotinib

EGFR Mut (+)

Recruiting

Recruiting

Status

Study

No.

PFS

PFS

PFS

OS

ORR

Safety

OS

QoL

ORR

Ongoing Study: erlotinib + bevacizumab

vs.

erlotinib as first-line treatment