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JO25567: PFS by independent review in all patients (primary endpoint)

75

72

69

64

60

53

49

38

30

20

13

8

4

4

0

77

66

57

44

39

29

24

21

18

12

10

5

2

1

0

T

A+T

Number at risk

0

0

1.0

Time (months)

4

8

12

2

6

10

14

18

22

26

16

20

24

28

0.2

0.4

0.6

0.8

PFS probability

9.7

16.0

Kato, et al. ASCO 2014

HR=0.54 (0.36–0.79)

Log-rank p<0.0015

Avastin + Tarceva

Tarceva