Can we select NSCLC patients for immune checkpoint therapy?

Common Pattern?

Bellmunt J, et al.

N Engl J Med.

2017;376(11):1015-1026; Ferris R, Gillison ML.

N Engl J Med.

2017;376(6):596; Borghaei H, et al.

N Engl J Med.

2015;373(17):1627-1639. Courtesy of Prof Besse

UROTHELIAL

KEYNOTE-045

LUNG

CHECKMATE-057

H&N

CHECKMATE-141

Curves cross,

suggesting a deleterious effect in a subgroup of patients

C EC TE-141