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0

3

6

9

12 15 18 21 24 27

0

10

20

30

40

50

60

70

80

90

100

Time, months

Overall Survival, %

60

57

55

51

46

44

36

22

7

1

63

58

57

51

43

39

29

18

9

0

No. at risk

Overall Survival

Data Cut-Off: May 31, 2017

a

24 additional deaths since primary analysis (pembro + PC, n = 7; PC alone, n = 17).

b

P value is descriptive (one-sided P < 0.025).

Median Follow-Up:

18.7 mo

Events,

n/N

HR (95% CI)

Pembro + PC

20/60

a

0.59

(0.34–1.05)

P

= 0.03

b

PC alone

31/63

a

77%

69%

Median (95% CI)

NR (22.8–NR)

20.9 (14.9–NR)

70%

56%

Hossein Borghaei

, et al. WCLC 2017

Crossover

~

75%