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Study
Drug
N
RR
Survival
ECOG
Doxorubicin
93
19%
8 mo
Doxorubicin + DTIC
95
13%
8 mo
SWOG
Doxorubicin + DTIC
79
32%
9 mo
Doxo + DTIC + cytoxan
95
35%
10.5 mo
ISSG
Doxorubicin + DTIC
170
17%
13 mo
MAID
166
32%
12 mo
EORTC
Doxorubicin
212
24%
12 mo
Doxorubicin + Ifosfamide
202
27%
12 mo
ECOG
Doxorubicin
90
20%
9 mo
Doxorubicin + Ifosfamide
88
34%
12 mo
GEIS
Doxorubicin
67
23%
26w/pfs
Doxorubicin + Ifosfamide
65
24%
24w/pfs
Higher RR but Same OS