SPIRITT
: Randomized P-II trial of FOLFIRI panitumumab or
bev after first-line FOLFOX/bev in
wt KRAS
mCRC
FOLFIRI/
PANITUMUMAB
n: 91
FOLFIRI/
BEVACIZUMAB
N:91
wt KRAS
mCRC pts
with PD after
BEV + oxaliplatin doublet
n: 182
Hecht JR et al. Clin Colorectal Cancer 2015