21 / 33
Oxnard, ASCO 2012; , Yu HA et al. JTO 2013
• 45% could delay change of therapy > 3mo after RECIST PD
• 21% delay change of therapy > 12mo
• Patients delaying change of therapy more commonly had no
cancer-related symptoms at PD and had no new metastases
Local Intervention for Oligoprogressive Disease
Median TTP 10 mo
Median OS 41 mo