23 / 64
OS by PD‐L1 expression: IMDC intermediate/poor risk
PD-L1 <1% (n = 562)
PD-L1 ≥1% (n = 214)
0.8
0.9
1.0
0 7
0.8
0.9
1.0
0 7
ty)
0.4
0.5
0.6
.
0.4
0.5
0.6
.
l Survival (Probabili
Median OS (95% CI), months
Median OS (95% CI) months
0.1
0.2
0.3
0.1
0.2
0.3
Overal
HR (95% CI), 0.73 (0.56–0.96)
P
= 0.0249
NIVO + IPI
NR (28.2
–
NE)
SUN
NR (24.0
–NE
)
HR (95% CI), 0.45 (0.29–0.71)
P
<0 001
,
NIVO + IPI
NR (NE
–NE
)
SUN
19.6 (14.8
–NE
)
23
0
6
12
18
27
33
0.0
3
9
15
21 24
30
0
6
12
18
27
33
0.0
3
9
15
21 24
30
Months
Months
284
251
223
200
76
0
278
239
198
157
61
1
100
87
83
76
33
2
114
90
72
55
21
2
NIVO
+ IPI
SUN
No. at Risk
.
Escudier B et al. ESMO 2017. Madrid