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PFS per IRRC: IMDC intermediate/poor risk

Median PFS (95% CI), months

1.0

HR (99.1% CI), 0.82 (0.64–1.05)

NIVO + IPI

11.6 (8.7–15.5)

SUN

8.4 (7.0–10.8)

al (Probability)

0.9

0.8

0.7

0 6

P

= 0.0331

sion-Free Surviv

.

0.5

0.4

0.3

Progres

0.2

0.1

0.0

0

3

6

9

12

15

18

21

24

27

30

425

304

233

187

163

149

118

46

17

3

0

422

282

191

139

107

86

57

33

11

1

0

No. at Risk

NIVO + IPI

SUN

Months

Motzer, SITC 2017