19 / 64
ORR and DOR: IMDC intermediate/poor risk
N = 847
O t
NIVO + IPI
N 425
SUN
N 422
Median duration of response
(95% CI), months
Patients with ongoing
response, %
NIVO + IPI
NR (21 8–NE)
72
u come
=
=
ORR
a
(95% CI), %
42
(37–47)
27
(22–31)
P
< 0 0001
0.9
1.0
y)
.
SUN
18.2 (14.8–NE)
63
.
BOR,
a
%
Complete response
Partial response
9
b
32
1
b
25
0.5
0.6
0.7
0.8
esponse (Probabilit
Stable disease
Progression
Not reported
31
20
8
45
17
12
0.1
0.2
0.3
0.4
Duration of R
a
IRRC-assessed confirmed ORR and BOR by RECIST v1.1;
b
P
< 0.0001
BOR, best overall response; DoR, duration of response; NE, not estimable; NR, not reached
0.0
0
6
12
18
24
Months
Motzer, SITC 2017