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OS by Prior Sunitinib and Prior Pazopanib Therapy in Patients With mRCC

HR (95% CI

), 0.81 (0.64–1.04)

Median OS, months

(95% CI)

Nivolumab

23.6 (20.4–28.1)

Everolimus

19.8 (17.5–24.3)

Prior sunitinib

HR (95% CI

), 0.60 (0.42–0.84)

Median OS, months

(95% CI)

Nivolumab

NE (19.7–NE)

Everolimus

17.6 (14.3–19.9)

Prior pazopanib

Based on data cut-off of June 2015.Motzer RJ et al. Oral presentation at ASCO GU 2016. 498

.

No. of patients at risk

Nivolumab

257

223

191

133

51

3

Everolimus

261

211

170

122

41

2

Overall Survival (Probability)

0

3

6

12

9

15

Months

18

21

24

27

30

33

Nivolumab

0.0

0.1

0.8

0.9

0.2

0.3

0.4

0.5

0.6

0.7

1.0

0

3

6

12

9

15

Months

18

21

24

27

30

33

Nivolumab

Everolimus

126

111

93

62

19

2

136

100

81

52

13

0

0.0

0.1

0.8

0.9

0.2

0.3

0.4

0.5

0.6

0.7

1.0

63%

49%

Everolimus

61%

54

%