Confirmed Objective Response Rate
Assessed per RECIST v1.1 by blinded, independent central review.
Data cut-off: May 9, 2016.
0
10
20
30
40
50
60
Pembrolizumab Chemotherapy
ORR, % (95% CI)
Pembro
Responders
n = 69
Chemo
Responders
n = 42
TTR, mo
median
(range)
2.2
(1.4-8.2)
2.2
(1.8-12.2)
DOR,
mo
median
(range)
NR
(1.9+ to
14.5+)
6.3
(2.1+ to
12.6+)
Δ17%
P
= 0.0011
45%
28%
PR
CR
n = 6
n = 63
n = 41
n = 1
Reck M, et al. NEJM 2016