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PSCA

(prostate stem cell antigen)

196

pts

Metastatic Panc Cancer

GS-1C4D4-Gem

Gem

1º endpoint: 6 m OS 60.9 %

p 0.03

40.4 %

median OS 7.6 m 5.5 m

RR 21.6 % 13.1 %

Rand. P. II with GS-1C4D4

(anti-PSCA mAb)

1

1.- Wolpin BM et al. Ann Oncol 2013