16 / 24
PALETTE: PFS by histological subtype
• Significant improvement in PFS demonstrated across each of the
three histological substrata
17
n (%)
PFS
Hazard
ratio
95% CI
p
value
Overall
369 (100%)
0.35
0.26, 0.48
<0.001
Leiomyosarcoma
158 (43%)
0.37
0.23, 0.60
<0.001
Synovial
38 (10%)
0.43
0.19, 0.98
0.005
Other STS
173 (47%)
0.39
0.25, 0.60
<0.001
Der Graaf W et al. Lancet 2012;379:1879-1886