© 2017 Eli Lilly and
Tap WD et al.
Lancet
2016;388:488-97 (updated 388:464)
Time (Months)
Olaratumb+Doxorubicin
Independent Review
Assessment
Olaratumab +
Dox
Dox
Patients/Events
66/37
67/34
Median, months
(95% CI)
8.2
(5.5, 9.8)
4.4
(3.1, 7.4)
HR (95% CI)
0.67 (0.40, 1.12)
Stratified p-value
.1208
Investigator
Assessment
Olaratumab +
Dox
Dox
Patients/Events
66/55
67/48
Median, months
(95% CI)
6.6
(4.1, 8.3)
4.1
(2.8, 5.4)
HR (95% CI)
0.67 (0.44, 1.02)
Stratified p-value
.0615
a
a
Met predefined criterion of α=0.20
PFS