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Development and External Validation of a Risk Assessment Model

(RAM) for Cancer-associated VTE

Two prospective cohorts: CATS & MICA cohorts

Development and external validation

Model with 2 variables:

Tumor site

D-dimer

The model discriminated well between

cancer patients with and without VTE

C-Index=0.67, 95% CI 0.64-0.68

C-Index=0.66, 95% CI: 0.58-0.72

Compared to KS:

Net reclassification improvement=0.44

Pabinger I et al, OC21.1, Berlin ISTH 2017

2 variables