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Median OS in

BRAF

Mutant 2nd-Line mCRC

1. De Roock W et al.

Lancet Oncol

. 2010;11:753-62; 2. Ulivi P et al.

J Transl Med

. 2012;10:87; 3. Peeters M et al.

J Clin Oncol

. 2014;32:5s (suppl; abstr 3557); 4. Saridaki Z et al.

PLoS One

.

2011;6:e15980; 5. Loupakis F et al.

BJC

. 2009;101:715-21

Retrospective evaluation of a limited dataset can only be hypothesis generating

Regimen

Number of Patients

Median OS, mo

Cetux-CT

1

24

6

Cetux-CT

2

12

5.8

FOLFIRI

3

23

5.7

FOLFIRI-Pani

3

22

4.7

Cetux-CT

4

8

4.3

Cetux-Iri

5

13

4.1

FOLFIRI

20

5.5

FOLFIRI-Aflib

16

10.3

VELOUR

Presented by Tejpar S at ESMO WGIC 2017