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Data cut-off: 12 June 2017

*Occurring in ≥15% patients

#

Grade unknown for one patient in SoC arm

ALT, alanine aminotransferase; AST, aspartate aminotransferase; SoC, standard-of-care

0

10

20

30

40

50

60

70

Incidence (%)

FLAURA: Similar if not better toxicity profile with osimertinib

Osimertinib

SoC

Ramalingam, ESMO 2017