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First Challenge: Harmonization of practices between platforms

Pembrolizumab

Nivolumab

Atezolizumab

Durvalumab

Hirsh, JTO 2017; Rimm DL, JAMA Oncol. 2017

Blueprint (n=39)

NCCN (n=90, multi-institutional)

Advanced NSCLC: several mAbs for each drug