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• TILs are correlated to favorable BC in ER- tumors
• TILs associated with better survival in early TNBC
• While PD-L1 protein expression is rare in breast cancer, it is
enriched in basal-like tumors
Nanostring Confidential (publication in process)
Ali HR, et al. Ann Oncol. 2015; Ibrahim EM, et al. Breast Cancer Res Treat. 2014; Matsumoto H, et al. Clinical Pathology, 2015; Zeng ,Oncotarget 2016
Role for TILs in different tumor types
• Meta-analysis. 24 studies (N=7.006 patients, stage I-IV)
• High CD3+, CD4+, or CD8+ TILs have been associated
with better prognosis