42 / 64
1ª línea: estudios en marcha
Catalyzes the
b kd f
NCT03260894
rea own o
tryptophan to
kynurenine leading to
suppression of CTL
1ª lí
Sunitinib o
pazopanib
and expansion of
Treg cells
nea
Random
Pembrolizumab
+
epacadostat
N=630
OP PFS OS
:
,
46 pac con C renal; RR 47%
Lara et al; ASCO 2017 #4515