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SafetyprofileCOU-AA-302vsPREVAIL trial
COU-AA-302
All grades (%)
Grade ≥3 (%)
ABI + P
Pbo + P
ABI + P
Pbo + P
Cardiac disorder
20
17
7
4
Hypertension
22
14
4
3
Fatigue
40
35
2
2
Rathkopf DE et al. Eur Urol 2014;66:815-25; Beer TM et al. N Engl J Med 2014;371:1424-33
PREVAIL
All grades (%)
Grade ≥3 (%)
ENZA (N=871)
Pbo (N=844)
ENZA (N=871)
Pbo (N=844)
Cardiac AE
10
8
3
2
Hypertension
13
4
7
2
Fatigue
36
26
2
2