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OS: IMDC intermediate/poor risk

Hazard ratio (99.8% CI), 0.63 (0.44–0.89)

P

< 0.0001

Median OS, months (95% CI)

NIVO + IPI

NR (28.2–NE)

SUN

26.0 (22.1–NE)

Overall Survival (Probability)

425

399

372

348

332

318

300

241

119

44

2

0

422

387

352

315

288

253

225

179

89

34

3

0

No. at Risk

NIVO + IPI

SUN

Months

1.0

0.9

0.8

0.7

0.6

0.5

0.4

0.3

0.2

0.1

0.0

18

21

24

27

30

33

15

12

9

6

3

0

Co-primary endpoint