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CTLs

B cells

Macrophages

(M1)

NK and ILC1s

B cells

Macrophages (M2)

Neutrophils

Myeloid suppresor cells

B cells

IFNγ

Grmz

ROS

Intracellular viruses, bacteria and tumors

Tissue repair to block large organism

Extracellular microorganism

Exclusion of microorganism

ILC2s

Eosinophils

IL-25

IL-33

TSLP

IL-1β

IL-23

ILC3s

Epithelial cells

(AMPs)