19 / 56
Adapted from Barrios CH, et al
. Breast Cancer Manage
2012.
Endocrine Therapy for HR
+
Breast Cancer
Estrogen receptor down-regulator
(SERD)
•
Fulvestrant (FUL)
Aromatase inhibitors (AIs)
Non-steroidal AIs
−
Anastrozole (ANA)
−
Letrozole (LET)
Steroidal AIs
−
Exemestane (EXE)
Selective estrogen receptor modulators (SERMs)
•
Tamoxifen (TAM)
•
Toremifene
mTOR Inhibitor
Everolimus
CDK 4/6 Inhibitors