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TILs+

PD-L1+

Type I

TILs-

PD-L1-

Type II

PD-L1-

TILs+

Type IV

PD-L1+

TILs-

Type III

Tumour Microenvironment

Teng MWL

et al

. Cancer Res 2015

Tumor microenvironment types based on TILs and PD-L1

TILs: Tumour-Infiltrating Lymphocytes