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RECIST vs CHOI EXPERIENCE

WITH SUNITINIB IN THE PHASE III STUDY

Mean tumour density

change in target lesions

(Choi)

Changes in tumour size

(RECIST)

Median TTP according to Choi criteria

Response evaluation after 4 weeks

of sunitinib treatment

Early occurrence of response by Choi criteria at the first tumour

evaluation may better identify than RECIST patients benefiting from sunitinib

Faivre S

et al. Targ Oncol

2012