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in Soft Tissue Sarcoma
Kawano S. el at. Mitotic and Non-Mitotic Effects of Eribulin Mesilate in Soft Tissue Sarcoma. Anticancer Research April 2016 vol. 36 no. 4 1553-1561
Eribulin induces morphological changes in STS cell lines
(A,B)
SW 872 Liposarcoma
MYLK, C/EBPβ, and KIF23 as
adipocyte differentiation marker
genes
(C,D)
SK-UT-1 Leiomiosarcoma
CNN1 as a smooth muscle
differentiation marker gene
“Eribulin treatment induces cellular differentiation down the
adipocyte and smooth muscle pathways, respectively”