Optimal First-Line Therapy for Advanced
ALK+ NSCLC
Crizotinib
Profile 1014
Ceritinib
ASCEND-3
1L
2L
11 months
18 months
(combined PFS)
Brigatinib
Ph 1-2
Alectinib
NP28673
Crizotinib
Profile 1014
Crizotinib
Profile 1014
24 months
(combined PFS)
21months
(combined PFS)
11 months
11 months