46 / 66
Edad (NSCLC)
Trial
Age
Regimen
N
HR for OS (95% CI) HR for PFS (95% CI)
Keynote 024
<65
>65
Pembro vs SOC
141
164
NR
NR
0.61 (0.40-0.92)
0.45 (0.29-0.70)
CheckMate
017
<65
65-74
>75
Nivo vs doc
152
91
29
0.52 (0.35-0.75)
0.56 (0.34-0.91)
1.85 (0.76-4.51)
0.62 (0.44-0.89)
0.51 (0.32-0.82)
1.76 (0.77-4.05)
CheckMate
057
<65
65-74
>75
Nivo vs doc
339
200
43
0.89 (0.70-1.1)
0.94 (0.69-1.27)
0.97 (0.49-1.95)
0.81 (0.62-1.04)
0.63 (0.45-0.89)
0.90 (0.43-1.87)
OAK
<65
>65
Atezo vs doc
453
397
NR
NR
0.80 (0.64-1.00)
0.66 (0.52-0.83)